So you packed your bag and got your 'before you go' shit together. But if you are heading out for the first time, it is not easy to understand exactly the factors you may deal with.
Now what will it be like 'on the road' when you get going? Once you understand them better you can stop worrying about your trip and where you are going, safe in the knowledge there is nothing [or little] to be worried about!
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Just allow time for it, and take the rough with the smooth, as it were - there is very little you can do about it once the poison is inside you apart from avoiding dehydration (Gatorade type sports drinks are much easier to drink than water and will replace a little energy/salt), get plenty of rest and let it come out of you (in whatever form - severe and continual vomiting that is preventing you from keeping water down and/or retching for long periods can be treated by tablets or an injection; either way consult a doctor if symptoms are persisting.
And remember keep your own hands clean before you eat.
Some of the easiest places to get ill are where there are large numbers of tourists and the locals have adapted by offering western type food and/or a lot of food is saved, stored and re-heated. You might never have a problem in India, eating Indian food, but suffer in Nepal eating western style food.
The latter is more serious and could be something much nastier.
There are literary dozens of different strains of both and it's pointless to cover them here, but most encountered (normally bacterial) aren't too serious.